Awareness in the importance of health benefits of testosterone in both men and women now has excellent research supporting its use.
To address widespread concerns regarding the medical condition of testosterone (T) deficiency and its treatment with T therapy, an international expert consensus conference was
convened in Prague, Czech Republic, on October 1, 2015 and was published in the Mayo Clinic Proceedings. Experts included a broad range of medical specialties including urology, endocrinology, diabetology, internal medicine, and basic science research.
Nine resolutions were debated, with unanimous approval: (1) TD is a well-established, clinically significant medical condition that negatively affects male sexuality, reproduction, general health, and quality of life; (2) symptoms and signs of TD occur as a result of low levels of T and may benefit from treatment regardless of whether there is an identified underlying etiology; (3) TD is a global public health concern; (4) T therapy for men with TD is effective, rational, and evidence based; (5) there is no T concentration threshold that reliably distinguishes those who will respond to treatment from those who will not; (6) there is no scientific basis for any age specific recommendations against the use of T therapy in men; (7) the evidence does not support increased risks of cardiovascular events with T therapy; (8) the evidence does not support increased risk of prostate cancer with T therapy; and (9) the evidence supports a major research initiative to explore possible benefits of T therapy for cardiometabolic disease, including diabetes.
These resolutions may be considered points of agreement by a broad range of experts based on the best available scientific evidence.